• 2 minutes
  • 17 September 2018

Urinary kryptopyrrole testing has been used since the 1960s to assist in the diagnosis and management of mental health disorders. Despite this long history of use, there has been minimal formal study into the validity of the testing. The Office of Research, in collaboration with SAFE Analytical Laboratories Pty Ltd (SAFE Labs), is seeking to establish a reference range for urinary kryptopyrroles in adults, enabling better patient management, and providing suitable data for registration of the test in Australia.

The Office of Research is conducting this research between February and August, 2018. There are four stages to this study, including a web based clinician survey, UKP sampling in adults with and without anxiety, and, a case control study. If you are seeking to participate in the study as an adult with or without anxiety, and can attend the Fortitude Valley campus, please see Stage 2 and 3 below.

Stage 1 - Retrospective survey of clinicians' experience of UKP testing

The survey has now closed (April 2018).This survey gathered data about clinicians' experience of UKP testing, observed disease states, and prescribed treatments. The purpose of this survey was to inform the choice of condition used in Stage 3 (see below). Thank you to all clinicians who participated in the survey.

Stage 2 and 3 - UKP levels in adults

Stages 2 and 3 of the study is about quantifying UKP levels in both adults who have no diagnosed health conditions, and, adults diagnosed with anxiety. The data collected from these two stages is central to the purpose of the whole study: to establish the reference range for urinary kryptopyrroles. This stage of the study is currently recruiting, and is estimated to be open to participation for the duration of February to August, 2018. Participation in the study requires visiting the Endeavour College of Natural Health Fortitude Valley campus three times, once per week on consecutive weeks, answering some brief questionnaires, and providing a urine sample for pyrrole analysis. Participants receive their UKP results and a $50 Coles-Myer gift card after participation. If you or someone you know may be interested in participating, please follow this link to complete the relevant pre-screening survey (links at the bottom of the page): https://www.endeavour.edu.au/research/ukp-study-2018

Stage 4 - Case control study

Finally in this series of stages, we are conducting an observational case control study of urinary kryptopyrrole levels in patients as managed by clinicians. You may find out more about this stage of the study here.

If you have any further queries, please contact the Office of Research.

This study has ethical clearance (Endeavour HREC #20171111).